The study, conducted by researchers at the University of Exeter in the UK, found that the number of senescent cells was reduced by as much as 50 percent.
British researchers have developed new compounds that can reverse the main aspects of aging human cells. For the study, the team targeted compounds – AP39, AP123 and RT01 – in the mitochondria (“powerhouse” cells).
The condition or worsening process involves selective compounds that generate small amounts of hydrogen sulfide gas in the mitochondria in the cells and have helped to become old or damaged, the “energy” necessary for survival and reduced cell senescence age.
“The newly developed compounds have the potential to alter the mechanisms by which cell aging occurs and compounds may open the door to new therapeutic approaches in the future, “said Professor Lorna Harries, from the Exeter University.
The results showed the possibility of future treatments not only for blood vessels that become stiffer with age but also for other cells. “This could be the foundation for a new generation of anti-degenerative drugs,” Harris said.
In addition, the goal should be for people to stay healthy longer. “It’s about the duration of your health and quality of life, rather than simply extending your life expectancy,” he said.
The study published in the journal “Aging, “the team used new chemicals and could play a key role in two splicing factors (or SRSF2 HNRNPD) in determining how and why cells specifically identify with age.
Many disease states can essentially be considered accelerated aging, and maintaining healthy mitochondria helps avoid or, in many cases, use animal models to reverse them, “said Lorna.